The rapid acceptance of immunohistochemistry as an important and even indispensable adjunct to morphological examination and diagnosis requires the modern anatomical pathology laboratory to be conversant with, and proficient in, immunostaining procedures, as well as methods of tissue processing and antigen retrieval and the underlying characteristics of the increasing number of antibodies and antisera available. This fully revised, expanded and updated edition provides a comprehensive list of antisera and monoclonal antibodies that have useful diagnostic applications in tissue sections and cell preparations. Various clones, which are commercially available to detect the same antigen, are listed and the sensitivities and specificities of the antibodies are discussed. Importantly, the authors, all pathologists with a wealth of experience in immunostaining procedures, provide fully referenced details and expert advice on each reagent, with the reader will find invaluable. Finally, the app
This fifth volume in an established series builds upon the success of previous volumes and presents a series of cutting-edge reports on the latest advances in pathology. The editors have brought together a team of expert contributors from around the world to present concise reviews of some of the most exciting recent developments in pathology practice and to point to possible future developments and applications of key techniques. Fully illustrated throughout, in colour where appropriate, this book is essential reading for all trainee and practising pathologists across the full spectrum of pathological sub-specialties.
Over the past three decades, there has been growing concern over the management of victims of trauma and of medical emergencies, not least in the standard of prehospital care which they receive. In the 21st century, there is an increasing requirement to transfer patients, by road and by air, to and from specialist centres of excellence or within hospitals from department to department as modern medicine dictates that the patient requires intra-hospital movement to an imaging scanner, to the operating theatre, and then perhaps to intensive care. This book is a practically based text in which the reader will find easy-to-digest details on clinical management and on the logistics of different transport modes as well as facts about the physics and physiology of patient movement. It is intended as a basic reference for those who seek to work in transportation medicine, primarily doctors, but it will prove of great relevance and interest to nurses, paramedics and those who administer
Multiple choice questions make up an important part of the MRCS Part 1 examination. QBase Surgery: 1 is much more than just a book as it also comes with a free CD-ROM. This powerful electronic package is installed easily and gives the reader a huge range of options to greatly enhance the value and utility of the book. Not only can the reader practice the set exams, but the CD-ROM will mark these exams, allow the reader to customize exams to focus in on areas requiring further revision, shuffle the stems to in effect set an inexhaustible number of different papers, and advise on examination strategy. It has the facility to print out and store the results and provide helpful notes on each question. This version of the QBase software (termed QBase+ for this title) has been modified to analyse the non-negatively marked MRCS MCQs and can be installed alongside the 'negatively marked' versions of the program already developed for the anaesthesia and medicine postgraduate examinations.
Key Facts in Clinical Nutrition provides, in a concise, fact-filled and pocket-sized format, all of the key information required by the general physician and nutrition specialist alike and covers everything from nutrition support and assessment, through nutritional and energy requirements, micronutrients, dietary supplements, enteral and parenteral nutrition and the role of the nutrition support team. A glossary of key terms is also provided, and useful appendices cover reference values for haematological, urine and faecal analysis, weight and height conversion charts, anthropometric measurements and key nutritional values.
Any healthcare professional with, or developing an interest in, clinical nutrition will be able to use this textbook as their sole source of information for the formation of a clinical nutrition support service of excellence. The first three parts of the book will enable a clear perspective of the metabolism and physiology of clinical nutrition to be related to the practical application of support techniques. The fourth part of the book highlights the role of nutrition support in specific disease groups. A number of additional chapters have been added, and modifications made to the content of chapters from the first edition to cover newer areas or areas of omission.
Even the most experienced clinician cannot be expected to remember all the relevant details of so many and varied uncommon problems of the seriously ill. Some of these problems can be overlooked in even a major Intensive Care textbook, most can be found eventually in specialist textbooks but the impact on intensive care management might well still be disregarded. This book offers a unique approach. Uncommon problems relevant to intensive care have been gathered into a single volume, in which they have been described in sufficient detail to avert much of the need to refer to specialized texts. Moreover, their implications for intensive care management have been highlighted. The book is intended to provide an easy and practical reference, alphabetically arranged, for the clinician at any level faced with such problems at the patient's bedside.
This book is designed specifically for candidates preparing for the MRCS Viva examination. The format of the exam has been used in the book's structure, with over 1000 questions to illustrate the key points of over 200 topics. The book has been divided into 6 main chapters corresponding to a viva 'station' in the exam. Each chapter begins with a check-list of the main topics and themes covered by the exam, and information is then subdivided logically within the chapter itself. Key 'pass-or-fail' concepts are covered, and in some cases, topics are covered in more detail than will be asked in the exam, so the candidate can be confident that they will be fully prepared.
Minimally invasive or laparoscopic surgery is becoming increasingly commonplace, as technology has enabled a minimally invasive approach to be offered as a feasible alternative to conventional open surgery for a number of important surgical procedures. This comprehensive, but concise and practically oriented introduction to the subject was first published in 2004 and will be of value to all anaesthetists with an interest in minimally invasive techniques. It begins by covering the key aspects of basic physiology, moves on to patient preparation and positioning, monitoring, the anaesthetic procedures themselves (including possible complications and contraindications and easy-to-follow 'how to' guides for a number of key procedures) and, finally, post-operative pain. Written by a leading expert in the field, from a well-known European centre of excellence, it is essential reading for anaesthetists and intensivists at all levels of expertise.
QNotes for the MRCP Part 1 works alongside the Royal College of Physicians published Part 1 MCQ papers from 1996 and 1997 (and more specifically the QBase CD-ROM that accompanied them) to provide the reader with explanatory note to each of the questions, which were not provided with the original CD-ROM or book. Whilst the notes are not approved in any way by the College, they are provided by a team of authors with recent experience of the MRCP MCQ examination and with considerable experience of teaching trainees themselves (Dr McCrudden also wrote QBase Medicine 2), and as such will provide an excellent basis for learning. All of the explanatory notes are comprehensive, and indexed to easily sourced texts to enable the reader to dig deeper into the topic if required. The CD installs the notes to the user's hard disk and when they then return to using the Royal College's MRCP QBase CD-ROM, the notes appear, linked seamlessly to each question in the usual way, and as if they were part of
The identification and proper classification of fractures is vital in determining the subsequent treatment and long term management of the patient. It is also an area of constant debate as to which system is the most comprehensive, systematic and easy to remember. This pocketbook uses specially generated line diagrams throughout to illustrate all of the major classification schemes currently used to identify fractures of the extremities. It is an essential quick reference for the trainee orthopaedic surgeon, both in the hospital environment and as a revision aid for the orthopaedic component of the MRCS examination, but it will also prove valuable to all personnel in the casualty environment, who need to be able to interpret and understand the different types of fracture and how different injuries affect patient management and subsequent clinical decision-making.
This book was written in response to legislation enabling nurses to prescribe and thus expand their role within the NHS. It is divided into 9 chapters examining in detail each of the groups of products described in the Nurse Prescribing Formulary (NPF). The authors have adopted a standardised chapter format throughout, beginning with a sound understanding of the basic pharmacology of each preparation, and building on this to incorporate relevant anatomical and physiological information, an examination of the modes of action of the drugs covered, as well as their doses, common side effects, and contraindications. Important issues related to patient assessment, evaluation and education are also highlighted. There is also an important opening chapter on the legal and professional aspects of nurse prescribing.
This concise integrated handbook looks at all available imaging methods for head and neck cancer, highlighting the strengths and weaknesses of each method. The information is provided in a clinical context and will guide radiologists as to the information the clinician actually needs when managing a patient with head and neck cancer. It will also provide the clinician with the advantages and limitations of imaging. The text therefore deals with Ultrasound, CT and MRI. The initial chapters aim to give the reader a core knowledge, which can be used in imaging by the various methods described. The subsequent chapters are directed towards clinical problems and deal with the common cancers in a logical order.
An authoritative handbook covering the management of all types of cancer, with an emphasis on those aspects of care of the cancer patient which are of particular interest in the community, for example the presentation of cancer and palliative care. The specialist management of different types of cancer is also covered, with particular regard being paid to the requirements of shared care in the community and the supportive care needed for the treatment of side effects and complications.
In the light of increased awareness of the legal as well as clinical implications of misdiagnosis of pathological specimens, this book provides the trainee and practising histo- and cytopathologist with a comprehensive review of the potential pitfalls encountered in a number of key diagnostic areas (cervical screening, breast cancer screening, pigmented lesions of the skin, lymphoproliferative disease, disease of the gastrointestinal tract and disease of the genito-urinary system). Each chapter has been written by a recognised expert in the organ or organ system concerned and, with the aid of full colour histo- and cytopathological specimens throughout, outlines the most important diagnostic and differential diagnostic features and indicates not only where confident diagnosis can sometimes prove problematic, but also how best to avoid these potential pitfalls in the first instance.
Severe acute respiratory syndrome (SARS) is a devastating disease and although the virus would appear to have been contained, it is clear that the impact it has had around the world, and could have again in the future, is immense. Hong Kong has been significantly impacted in the recent SARS outbreak, and clinicians and researchers alike have gained a lot of experience in dealing with the disease at short notice. This new book aims to be a state-of-the art update on SARS, with particular reference to imaging, which plays a crucial role in the diagnosis, management and follow-up of patients with the disease (it is widely accepted that SARS patients cannot be managed without imaging and it is included in the WHO's own list of diagnostic criteria for the disease). The book will also provide a perspective on the treatment and experience of the disease outside Hong Kong.
Developments in biochemistry have contributed immensely to the rate at which medical knowledge has expended in recent years. Following the GMC recommendations regarding undergraduate medical education, Biochemistry for Clinical Medicine integrates, in a single volume, all aspects of biochemistry required by a medical student, with a special focus on information specific to medicine as opposed to laboratory-based biochemistry. The first section of the book provides an understanding of basic cell biology and the critical concepts of membrane transport, cellular energetics, information storage, transmission and expression, as well as describing the essential chemistry and metabolism of cellular biomolecules and the clinical conditions that arise from disturbances in their metabolism. The second section adopts a systems-based approach to present clinical biochemistry in an easily readable and concise manner, using tables and clear diagrams to summarise important facts, as well as
The need for specialist knowledge of the laws governing the regulation of medicines has become apparent. This is the case among not only lawyers but also hospitals, researchers, prescribers and many others involved in the provision of healthcare. Such a need has been precipitated by a number of factors, including the changing structure of healthcare in the UK and Europe and the various changes in regulation that have arisen both from challenges in the courts and from the intervention of public bodies. However, the information available to those involved in the complex interrelations between medicines, medical devices and the law have remained scarce. This book aims to address this situation by bringing together the knowledge of the laws governing the regulation of medicines ranging across the field from the ethics of the use of medicines in treatment and research, through to drug-induced injury, civil liability and no-fault compensation schemes.
This new and fully updated edition of Anaesthetic Aide-Memoire provides a compilation of key lists, numerical data, physiological and pharmacological formulae, procedural algorithms, important information on illnesses pertaining to anaesthesia, data on equipment, clinical measurement, and intensive care management that will serve as a valuable quick reference for senior anaesthetists in training and for consultants in anaesthesia. It is the ideal first reference source to consult when a fact, statistic, or formula eludes the memory, and as such will also prove to be a useful aid to teaching. It will also be useful for candidates for the FRCA examination who will already understand the basic physiology and pharmacology underpinning anaesthesia but who need reminding occasionally in a clear, concise, didactic way.
Clinical decisions in modern medical practice are increasingly influenced by ethical and legal issues, but few doctors have been formally trained in medical law and ethics, and are unsure of potential sources of accessible information, which leaves them exposed to public criticism and the threat of legal action. Perioperative medicine and critical care are, by their very nature, subjects in which issues of autonomy, dignity, consent, confidentiality, medical research, life and death decision making, and the rationing of health care resources are ever-present. This book provides a straightforward but comprehensive one-stop reference and should be essential reading for all medical and allied health care professionals who encounter ethicolegal problems during their management of patients.
