This volume presents a list of cutting-edge protocols for the study of CRISPR-Cas defense systems and their applications at the genomic, genetic, biochemical and structural levels. CRISPR: Methods and
The purpose of the Parathyroid Diseases and Calcium Disorders: A Case-Based and Practical Guide is to present a comprehensive and concise overview of our current knowledge in the area of parathyroid
This detailed volume covers a wide variety of techniques either developed specially for plant senescence studies or optimized for studying senescing plants. After an introduction to the topic, the boo
Alzheimer’s disease (AD) and many other neurodegenerative disorders are multifactorial in nature, involving a combination of genomic, epigenomic, network dynamic and environmental factors. A proper in
This book expands on the previous volumes with new chapters exploring emerging themes and methodologies in bacterial virus research. The chapters in this book are divided into 4 parts and cover topics
In Hormone Therapy in Breast and Prostate Cancer, many of today's leading researchers and clinicians describe the principles underlying targeted hormonal treatments, assess the actions of new and esta
Chemical pesticides continue as a point of major controversy in our society. Increasingly stringent regulatory actions on the part of state and federal agencies, exemplified by the RPAR (Rebuttable Pr
Systems Biology aims at deciphering the genotype-phenotype relationships at the levels of genes, transcripts (RNAs), peptides, proteins, metabolites, and environmental factors participating in complex
The past few years have seen the emergence of a growing, widespread desire in this country, and indeed everywhere, that positive actions be taken to restore the quality of our environment, and to prot
With the exception of a few tropical medicine schools worldwide, current medical education programs include almost zero discussion of the interface between infectious diseases and entomology. Th
The police composite sketch, one of the most crucial investigative tools in law enforcement, is developed during a composite session—an intense display of communication and art in which the words of a
This fully updated second edition explores protocols that address the most challenging aspects of experimental work in ancient DNA, such as preparing ancient samples for DNA extraction, the DNA extrac
This book expands on the previous volumes with new chapters focusing on functional characterization of phage and their proteins, and on the development of phage therapy by outlining novel models. The
This volume details a collection of state-of-art methods including identification of novel ncRNAs and their targets, functional annotation and disease association in different biological contexts. Cha
This volume explores and explains how digital PCRs (dPCRs) help in the study of numerous topics, such as infectious diseases, evolution of cancer and treatment responses, somatic mosaicism, genome edi
