Molecular Principles of Fungal Pathogenesis

Inspired by the their teaching of the molecular mycology course at Woods Hole, the editors have selected a comprehensive set of papers describing the most current research, including genome projects, genetics and molecular biology as well as potential vaccines and therapies. The collection begins with general principles, including the need to study fungal molecular pathogenesis, the evolution of fungal virulence, postgenomic strategies, mating and parasexual genetics, cell identity, and molecular principles of antifungal drug resistance. They describe model systems, including heterologous hosts, model pathogens and fungal-bacterial interactions, specific pathogens such as Candida albicans, pneumocystis and black molds, the host, including innate and acquired cellular immunity to fungi, interactions and fungal vaccine development and future directions, including genomics and proteomic analysis. Suitable for professionals as well as students, the text is well-illustrated. Annotation c2006 Book News, Inc., Portland, OR (booknews.com)