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本書內容設置新穎，有別於國內的任何分子生物學教材，按以下4部分展開：結構、功能、協調及實驗操作。其內容和版式已被美國印第安那大學數百名學生選用並幾經修訂，本書為第三版。適用於生物學專業分子生物學課程教材，為學習高級分子生物學奠定堅實的基礎。EssentialsofMolecularBiologyisintendedtobeusedforashortfirstcourseinmolecularbiology.Thethirdeditionretainsthebrevityofpresentationandemphasisonfundamentalsthatcharacterizedpreviouseditionsandwillprovidestudentswiththebasicfundamentalsofmolecularbiology.ThecontentandformatofthisbookwereextensivelyfieldtestedbyhundredsofundergraduatestudentsatIndianaUniversitythroughouttherevisionprocess.Keyconceptsarehighlightedineachchapter,sothatthetopicsbeingdevelopedarestatedconcisely.Factualcontenthasbeenupdatedthroughout.Thetextemploysthe搇ayering?approachtoknowledgeconstruction.Complexityisdevelopedchapterbychapter,ratherthanpresentedallatonceinaseriesofdetail-ladendescriptions.Anewchapterhasbeenaddedtothethirdedition-"MolecularBiologyIsExpandingItsReach"(Chapter16)Progressiondiagramshavebeenaddedtomostchapterstoserveasa"roadmap"forthestudent.
目次
Prologue
Preface
Introduction
Chapter1 Welcome to Molecular Biology!
The Structure of Proteins,Nucleic Acids,and Macromolecular Complexes
Chapter2 Macromolecules
Chapter3 Nucleic Acids
Chapter4 The Physical Structure of Protein Molecules
Chapter5 Macromolecular Interactions and the Structure of Complex Aggregates
Function of Macromolecules
Chapter6 The Genetic Material
Chapter7 DNA Replication
Chapter8 Transcription
Chapter9 Translation
Chapter10 Mutations,Mutagenesis,and DNA Repair
Coordination of Macromolecular Function in Cells
Chapter11 Regulation of Gene Activity in Prokaryotes
Chapter12 Bacteriophage
Chapter13 Regulation of Gene Activity in Eukaryotes
Experimental Manipulation of Macromolecules
Chapter14 Plasmids and Transposons
Chapter15 Recombinant DNA and Genetic Engineering:Molecular Tailoring of Genes
Chapter16 Molecular Biology Is Expanding Its Reach
Appendix Chemical Principles Important for Understanding Molecular Biology
List of Essential Concepts of Molecular Biology
Glossary
References for Further Reading
Answers to Queations and Pronblems
Index
Preface
Introduction
Chapter1 Welcome to Molecular Biology!
The Structure of Proteins,Nucleic Acids,and Macromolecular Complexes
Chapter2 Macromolecules
Chapter3 Nucleic Acids
Chapter4 The Physical Structure of Protein Molecules
Chapter5 Macromolecular Interactions and the Structure of Complex Aggregates
Function of Macromolecules
Chapter6 The Genetic Material
Chapter7 DNA Replication
Chapter8 Transcription
Chapter9 Translation
Chapter10 Mutations,Mutagenesis,and DNA Repair
Coordination of Macromolecular Function in Cells
Chapter11 Regulation of Gene Activity in Prokaryotes
Chapter12 Bacteriophage
Chapter13 Regulation of Gene Activity in Eukaryotes
Experimental Manipulation of Macromolecules
Chapter14 Plasmids and Transposons
Chapter15 Recombinant DNA and Genetic Engineering:Molecular Tailoring of Genes
Chapter16 Molecular Biology Is Expanding Its Reach
Appendix Chemical Principles Important for Understanding Molecular Biology
List of Essential Concepts of Molecular Biology
Glossary
References for Further Reading
Answers to Queations and Pronblems
Index
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