In the clinical neurosciences, decision-making becomes ever more complicated because of rapidly emerging new diagnostic tests and treatments and increasing demands from patients to participate in their management. This concise but wide-ranging handbook reviews the epidemiology of neurological disease and the treatment and prognosis of all major diseases of the nervous system. Part one offers essential guidance for clinicians to quantitative methods in research, including genetic epidemiology, decision analysis, meta-analysis, outcomes research and survival analysis, and thus provides a good understanding of the evidence underlying clinical management. The second part is devoted to individual neurological diseases, covering etiology, diagnosis, prognosis, interventions, and implications for clinical practice. With contributions from leading international authorities, this book is an invaluable guide to clinical decision-making for neurologists and others involved in the management of ne
Over the past fifty years, the case-control method, and to a lesser extent its case-based variants, have become the most important tools for the investigator of health problems. The case control meth
