M. G. Myriam Hunink (EDT)/ Paul Glasziou/ Joanna E. Siegel/ Jane C. Weeks/ Joseph S. Pliskin/ Arthur Shirle Elstein/ Milton C. Weinstein/ M. G. Myriam Hunink
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Decision making in health care involves consideration of a complex set of diagnostic, therapeutic and prognostic uncertainties. Medical therapies have side effects, surgical interventions may lead to complications, and diagnostic tests can produce misleading results. Furthermore, patient values and service costs must be considered. Decisions in clinical and health policy require careful weighing of risks and benefits and are commonly a trade-off of competing objectives: maximizing quality of life vs maximizing life expectancy vs minimizing the resources required. This text takes a proactive, systematic and rational approach to medical decision making. It covers decision trees, Bayesian revision, receiver operating characteristic curves, and cost-effectiveness analysis, as well as advanced topics such as Markov models, microsimulation, probabilistic sensitivity analysis and value of information analysis. It provides an essential resource for trainees and researchers involved in medical
A textbook for graduate students and tutorial for health-care professionals that shows how to integrate quantitative, evidence-based data and subjective outcome values in making clinical and health- p
