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黃皮醯胺的化學和生物學活性(簡體書)
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黃皮醯胺的化學和生物學活性(簡體書)

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張均田主編的《黃皮酰胺的化學和生物學活性(全英文版)(精)》共15章,反映了黃皮酰胺研究的熱點和最新進展。本書由我國著名藥理學家張俊田教授組織編寫,國內相關專家對其所擅長的領域編寫,各章具有較高學術水平。本書可供從事相關新藥研究的科研人員參考閱讀。

名人/編輯推薦

張均田教授又一力作《《黃皮酰胺的化學和生物學活性》》,反映了黃皮酰胺的研究水平,是研究人員的重要參考和啟發之作。

目次

Overview: Recent Advances in the Study of (-)Clausenamide on Chemistry,
Biological Activities and Mechanism of Action 1
The Synthesis of Clausenamide Family Natural Products and Analogues 14
Pharmacological Activity of Clausenamide as A Chiral Drug 33
Neuroprotection of (-)Clausenamide via Inhibiting Tau Hyperphosphorylation
and Preserving Microtubule Structure 49
Synaptic Pharmacology of Clausenamide 64
Two Forms of Long-term Potentiation Induced by (-)Clausenamide and Rgl 73
The Nootropic Mechanism of (-)Clausenamide 80
Mechanism of (-)Clausenamide Induced Calcium Transient in Primary Culture
of Rat Cortical Neurons 85
(-)Clausenamide Enhances the Synaptic Plasticity through Gasotransmitters 96
Antiapoptotic Effect of (-)Clausenamide and its Mechanisms of Action 107
The Signal Transduction Pathway of (-)Clausenamide on Activation of
Learning and Memory 114
Overview: Recent Advances in the Study of (-)Clausenamide on Chemistry,
Biological Activities and Mechanism of Action 1
The Synthesis of Clausenamide Family Natural Products and Analogues 14
Pharmacological Activity of Clausenamide as A Chiral Drug 33
Neuroprotection of (-)Clausenamide via Inhibiting Tau Hyperphosphorylation
and Preserving Microtubule Structure 49
Synaptic Pharmacology of Clausenamide 64
Two Forms of Long-term Potentiation Induced by (-)Clausenamide and Rgl 73
The Nootropic Mechanism of (-)Clausenamide 80
Mechanism of (-)Clausenamide Induced Calcium Transient in Primary Culture
of Rat Cortical Neurons 85
(-)Clausenamide Enhances the Synaptic Plasticity through Gasotransmitters 96
Antiapoptotic Effect of (-)Clausenamide and its Mechanisms of Action 107
The Signal Transduction Pathway of (-)Clausenamide on Activation of
Learning and Memory 114
Pharmacokinetics and Metabolism of Clausenamide Enantiomers 119
Metabolic Transformation of Clausenamide 142
Preclinical Safety Evaluation and General Pharmacology of (-)Clausenamide 148
Optical Separation and Quality Research of Clausenamide Enantiomers 157
Abstracts in English and Chinese 173

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