微納技術著作叢書：生物微機電系統（簡體書）

微系統技術領域的飛速發展為許多重點學科(從微電子到生命科學)引入了極具前景的產品，特別是生命科學和衛生保健業，一直是人們期望的微系統技術產品的主要市場。毫無疑問，生物學和微納科學的結合將會制造一場新的科技革命。器件的微型化，直到納米級別，接近生物組織的大小，將是生命科學成功的必備條件。從長遠角度來看，生物技術和微納技術的結合將使人們對細胞和整個生物體的功能有更深的見解。本書對生物微系統進行了簡單的回顧，并把微納米技術廣泛滲透到生物和醫學領域，這對未來科學和生命科學新產品的發展進程是十分必要的。 本書適于生命科學、系統生物學、生物工程學和微納米系統工程等相關領域的大專院校教師、高年級學生、研究生及科技人員閱讀參考。

Contributing Authors
Preface
EARLY BIOMEMS MULTI-SENSOR NEUROPROBES
　1.INIRODUCTION
2.EVOLUTION OF MICRO-SENSOR ARRAY DESIGNS
2.1 Electrical signal monitoring
2.2 Sensor Design monitoring
2.3 Chamber Type of Electrochemical 2D to 3D
3.OTHER APPLICATIONS-THE FIRST MICRO-FLUIDIC DEVICE
4.CONCLUSION
5.REFERENCES
MULTI-PARAMETER BIOMEMS FOR CLINICAL MONITORING
1.INTRODUCTION
2.BIOSENSORS
2.1 Prinsiple of Biosensors
2.2 Amperometric Biosensors
3.CLINICAL MONITORING
3.1 Multi-analyte measurement
3.2 Micro-dialysis
3.3 BioMEMS for clinical monotoring
3.4 Multi-parameter monitoring
3.5 Application
3.5.1 Monitoring of glucose and lactate with a micro-dialysis probe
3.5.2 Ammonia monitoring
4.CONCLUSIONS AND OUTLOOK
5.REFERENCES
NEURAL IMPLANTS IN CLINICAL PRACTICE
Interfacing neurons for neuro-modulation, limb control,
and to restore vision-Part I
1.INTRODUCTION TO NEURAL IMPLANTS
2.ANATOMICAL AND BIOPHYSICAL FUNDAMENTALS
2.1 Preipheral Nerve Anatomy
2.2 Mechanisms of peripheral Nerve Damage
2.3 Extra-celluar Stimulation of Nerve Fibres
2.4 Electrical Modelling of the Nerve Membrane
2.5 Propagation of Action potentials
2.6 Extra-cellular Stimulation of Nerve Fibress
2.7 Selective Activation of Neve Fibress
……
BIOMEDICAL MICRODEVICES FOR NEURAL IMPLANTS
Interfacing neurons for neuromodulation, limb control,
and to restore vision-Part II
MICRO-FLUIDIC PLATFORMS
DNA BASED BIO-MICRO-ELECTRONIC
MECHANICAL SYSTEMS
SEPARATION AND DETECTION ON A CHIP
PROTEIN MICROARRAYS: TECHNOLOGIES
AND APPLICATIONS
LAB-ON-A-CHIP SYSTEMS FOR CELLULAR ASSAYS
NETWORK ON CHIPS
Spatial and temporal activity dynamics of functional networks
in brain slices and cardiac tissue
BIO-NANO-SYSTEMS
Overview and Outlook